Business Wire

“Test the Taste”, a Special Event for PKU Patients: Enjoying Food Thanks to APR Innovative Supplementation

Del

APR Applied Pharma Research s.a (APR), the Swiss developer of science driven and patent protected healthcare products, is pleased to share the success of a special event, “Test the taste”, addressed to Phenylketonuria (PKU) patients and organized with the purpose of allowing them to test the company innovative Phenylalanine (Phe)-free medical food for PKU management.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20180712005363/en/

Thumbs up from patients and families on APR's innovative medical food for PKU (Photo: APR)

Thumbs up from patients and families on APR's innovative medical food for PKU (Photo: APR)

The initiative, promoted by the APMMC, the Italian patients association of inherited metabolic diseases with the unconditioned support of APR, aimed at gathering genuine feedbacks from PKU patients and their families on the company innovative medical food palatability in a friendly and relaxed setting - a Sunday lunch.

During the lunch, a well-known chef prepared, under medical supervision, a full menu suitable for a PKU diet, made of four dishes - from appetizer to dessert, each of them including APR Phe-free amino-acids (AA) supplementation.

After each course, patients and caregivers, who did not receive any information about the company innovation, were asked to assess the supplemented food just enjoyed (under medical guidance) as per texture, odor, taste and after-taste by filling out a brief questionnaire. For a complete evaluation, appetizer was served twice, with and without APR’s Phe-free AA mix, to allow the audience to better grab the differences.

Responses from both patients and families are extremely positive: no remarkable differences were reported in terms of odor and taste after sampling the appetizer with or without the AA mix.

According to the guests, APR innovative Phe-free supplementation did not affect the overall food taste and odor as the opinions expressed on the dishes served mostly referred to either the flavor or the texture of the ingredients regardless of the AA mix. The most noticeable feedback is the one regarding the aftertaste of the AA mix, which, as reported by PKU patients, could impact negatively their food experience: APR Phe-free AA mixture was markedly appreciated.

“At last thanks to APR’s new AA mix we have the chance to enjoy a delicious lunch without worrying about odor, taste and aftertaste of the supplementation.” said a patient who participated to the initiative “Food palatability was really great and we are eager to test this innovative AA mix a variety of recipes! We hope to find soon APR’s AA mix available as it can help us as patients to achieve a lasting and rewarding compliance to the compulsory dietary regimen”.

“As father of a PKU teenager and having gone through the troubles of a strict long-life dietetic treatment, we are very proud to offer to patients a new perspective of quality of life. Our dream is to make a real difference for those who live and deal with PKU.” said Paolo Galfetti, CEO of APR.

APR’s innovative and patented Physiomimic Technology® is able to remarkably mask the naturally unpleasant taste and the odor of some amino acids, offering a considerably palatable medical food, which can be easily accepted by patients, thus supporting their compliance and impacting positively their quality of life.

On the other side, as shown in a recent kinetic study, APR’s advanced formulation of AAs, by providing amino acids in more physiological manner (mimicking that of dietary proteins), has the very encouraging potential of contributing to maintain Phe levels within the recommended ranges, with less prominent fluctuations of Phe over time, thanks to a prolonged release of AAs in the gut.

Further preclinical studies as well as clinical evidences are underway to reinforce the scientific profile of the innovative medical food.

APR will present officially its new range of Phe-free medical food for PKU dietary management, as well as new original scientific data, at the next Annual Symposium of the SSIEM (Society for the Study of Inborn Errors of Metabolism) on September 4th-7th in Athens, which will be the occasion for attendees to get to know APR’s innovation and the patented technology behind it.

About Phenylketonuria or PKU

Phenylketonuria or PKU is a rare, genetic, recessive metabolic disorder affecting about 50.000 people worldwide. PKU is characterized by the deficiency or the malfunctioning of a liver enzyme needed to process phenylalanine (“Phe”), an essential amino acid found in most protein-containing food. Excessive amounts of Phe in the bloodstream become toxic to the brain, impairing the normal development of the central nervous system. If not properly treated, PKU leads to severe, non-recoverable mental retardation and major cognitive disabilities. PKU can only be treated through a strict, life-long, low-protein (low-Phe) dietetic treatment combined with a daily assumption of low-protein modified foods and medical food, which provides Phe-free amino acids and other important nutrients, needed due to the dietary restrictions of PKU patients.

About APR Applied Pharma Research s.a.

APR is a Swiss, independent developer of science driven, patent protected healthcare products. The Company identifies, develops and licenses, value added products designed to address patient or consumer needs in niche or rare therapeutic areas on a global basis. In particular, APR’s business model is currently focused on two pillars: (i) internally developed and financed (alone or together with co-development partners) proprietary, value added products to be licensed to healthcare companies for their commercialization, and (ii) support to third party projects by offering added value R&D services under contract and fee for service arrangements. APR has a balanced pipeline of revenue generating branded products marketed in all major markets, combined with a compelling pipeline of products at different stages of development. APR has entered into licensing and partnership agreements with pharmaceutical companies in over 70 countries, with international sales on a worldwide basis.

For more information about Physiomimic™ Technology, please visit: www.apr.ch/apr-pharmaproducts/medical-prescription/genetic-metabolic-disease/

Contact information

APR Applied Pharma Research s.a.:
Paolo Galfetti, Chief Executive Officer
paolo.galfetti@apr.ch
+41 91 6957020

Om Business Wire

Business Wire
Business Wire
24 Martin Lane
EC4R 0DR London

+44 20 7626 1982http://www.businesswire.co.uk

(c) 2018 Business Wire, Inc., All rights reserved.

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Følg saker fra Business Wire

Registrer deg med din epostadresse under for å få de nyeste sakene fra Business Wire på epost fortløpende. Du kan melde deg av når som helst.

Siste saker fra Business Wire

Dimension Data Global Delivery Centre (GDC) in Prague wins the ABSL 2018 Diamond Award for Business Innovation16.11.2018 08:00Pressemelding

Dimension Data, the USD 8 billion global technology integrator and managed services provider, today announced that its Global Delivery Centre (GDC) in Prague has won the 2018 ABSL Diamond award for Business Innovation. The main purpose of this centre is to provide innovative, global service delivery capabilities and deep technical expertise to support our clients. The ABSL Diamond awards recognise companies that implement innovative projects, enhancing their business and strengthening the position of the business services sector. Every year, the aim is to identify successful activities in this sector and promote best practices, ultimately encouraging and inspiring others to follow suit. The ABSL celebrates initiatives that push business services forward and stand out as exemplary projects. Bill Padfield, Group Chief Operating Officer for Transformation and Services at Dimension Data, said: “Winning another award for our Support Services is a fantastic achievement. This time the ABSL Di

FCC Grants LeoSat U.S. Market Access16.11.2018 06:00Pressemelding

LeoSat Enterprises, the dynamic young company which is launching a unique new data network comprised of a constellation of up to 108 low-earth-orbit communications satellites, has been awarded the authority by the U.S. Federal Communications Commission (FCC) to provide NGSO (non-geostationary satellite orbit) services in the United States. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181115005890/en/ LeoSat's Global Business Backbone in Space (Graphic: Business Wire) The increasing demand for business connectivity and with it, the need to move large quantities of data quickly and securely around the world, is fast outpacing the infrastructure in place to carry it. Existing networks are already carrying more than 1 Zeta Byte of traffic globally and this is set to grow exponentially. The FCC market access grant will allow LeoSat to address currently unmet demand for high-bandwidth, low-latency, high-security data transmissio

German Court Rules Huawei, ZTE Products Infringe AVC Patents16.11.2018 05:01Pressemelding

MPEG LA announced today that the District Court in Düsseldorf, Germany (“Landgericht Düsseldorf”) has ruled that Huawei Technologies Deutschland GmbH (“Huawei”) and ZTE Deutschland GmbH (“ZTE”) infringed patents of two patent holders in MPEG LA’s AVC Patent Portfolio License (“AVC License”) by using their technologies in mobile phones that implement the AVC/H.264 (MPEG-4 Part 10) Standard. The court also found that the license offered by the patent holders under those patents through the AVC License is fair, reasonable and nondiscriminatory. “The Landgericht Düsseldorf’s decision confirms the importance of respect for intellectual property, and offering everyone easy and affordable access to essential AVC technology under a single license is a cornerstone of the MPEG LA AVC License’s wide acceptance making that possible,” said Larry Horn, President and CEO of MPEG LA. “We continue to welcome Huawei and ZTE to join the nearly 2,000 Licensees who have entered into our AVC License.” Verdi

IFF-LMR Naturals Leads Industry with 90 Certified Vegan Natural Extracts15.11.2018 21:15Pressemelding

Regulatory News: IFF-LMR, a subsidiary of International Flavors & Fragrances Inc (NYSE:IFF) (Euronext Paris: IFF) (TASE: IFF) announced their industry-leading position of 90 natural extracts in their portfolio certified vegan by the EVE (Expertise Vegan Europe) VEGAN standards. The certified extracts include Rose EssentialTM, Rose UltimateTM, Blackcurrant Buds Absolute, Ylang Oil Complete, Vetiver Oil Haiti, Patchouli Oil Indonesia, and Geranium Heart Oil, among many others. Bertrand de Preville, General Manager, IFF-LMR said, “Our people are passionate about creating the finest ingredients and together, we are committed to delivering premium, 100% pure and natural extracts. We believe in transparency, environmental management and sustainable development.” Mr. de Preville continued, “This certification of 90 extracts is in line with IFF-LMR’s continuous dedication to our planet, people, plants and animals.” The EVE VEGAN label was selected because it is considered one of the most rigor

Rimini Street Expands Investment and Operations in Asia-Pacific15.11.2018 20:00Pressemelding

Rimini Street, Inc. (Nasdaq: RMNI), a global provider of enterprise software products and services, and the leading third-party support provider for Oracle and SAP software products, today announced that it has expanded its operations in the Asia-Pacific region with the launch of its new subsidiary, Rimini Street New Zealand Limited, and the opening of its new office in Auckland to address the growing demand for Rimini Street’s premium, ultra-responsive support services in New Zealand. Rimini Street’s expansion was announced at a gala event held at The Northern Club in Auckland, where clients, local IT leaders and the special guest of honor, Ambassador Scott P. Brown, the U.S. Ambassador to New Zealand, were hosted by Rimini Street’s general manager for Asia-Pacific, Andrew Powell, and Rimini Street corporate senior executives. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181115005037/en/ Rimini Street launches subsidiary

Sartorius Stedim Biotech and Lonza Modify Relationship for Supply of Cell Culture Media15.11.2018 18:15Pressemelding

Sartorius Stedim Biotech (SSB) (Paris:DIM), a leading international supplier of the biopharmaceutical industry, and Lonza announced today that they have modified their current agreement for supply of cell culture media by mutual accord. The agreement, signed in 2012, gave SSB exclusive sales and marketing rights for certain cell culture media and buffers developed and manufactured by Lonza for use in biopharmaceutical manufacturing processes. Lonza retained sales for research-based products, among others. Under agreements signed today, SSB will continue to offer current and future Lonza media and buffers on a non-exclusive basis as part of its extensive portfolio of products for cell-based development and manufacturing. Lonza Pharma & Biotech resumes sales and marketing of all its media products for both manufacturing and research. Customers of both companies will continue to be able to source media products for their specific needs. “We have a long-standing and productive partnership