Business Wire

SAB Biotherapeutics' Immunotherapy Proposal among Top Platform Technology Solutions in WHO Report

Del

SAB Biotherapeutics (SAB), a clinical-stage biopharmaceutical development company, announced today that its DiversitAb human antibody production platform, leveraging transchromosomic cattle (Tc Bovine™), was identified as of one of the six most meritorious proposals emerging from the World Health Organization (WHO) public consultation on platform technologies for priority infectious diseases with epidemic potential.

This consultation was part of the WHO Research & Development Blueprint, a global strategy and preparedness plan that allows the rapid activation of R&D activities that can be used to save lives and avert large-scale crisis during epidemics. SAB Biotherapeutics’ technology was the only immunotherapy platform among the six finalists (of 35 proposals), which also included three vaccine platforms, a diagnostic technology and a technology covering all product streams.

In October 2015, SAB submitted their proposal, “Targeted Human Immunoglobulin to WHO Priority Pathogens Using Transchromosomic (Tc) Bovine,” which outlined a project over a two-year period to increase their response capability, leveraging a dedicated herd of human antibody producing cattle, to be readily available should an outbreak occur. When needed, the Tc Bovine could be utilized to quickly develop, test, manufacture product and submit to regulators in order to halt the outbreak and help save lives. Targeted human polyclonal immunoglobulins produced in the platform would allow for new solutions and provide an approach that is quickly scalable to be an effective global response.

The WHO sought to identify the most promising R&D platform technologies to combat their priority pathogens including Ebola and MERS, as well as other diseases with epidemic potential such as Zika and Dengue, through a multi-step evaluation process.

“Two key benefits of our unique technology platform are its ability to respond rapidly and produce potent fully-human antibodies to a wide variety of disease targets, including viruses, bacteria, and toxins, in significant quantities,” said Eddie Sullivan, Ph.D., SAB Biotherapeutics president and CEO. “In addition, we have sought to focus our efforts on pathogens including those of priority to the WHO, and have completed several successful studies targeting those potential epidemic threats.”

Proposals were evaluated by an ad hoc Advisory Group (AG) comprising world-renowned experts from medical, scientific and regulatory backgrounds–on their ability to develop and manufacture solutions for clinical trials, in months rather than years, against a variety of infectious disease threats. Other criteria included a favorable benefit-risk profile, scalability, ability to produce sufficient quantities, deliver to low- and middle-income countries (LMICs) and affordability.

The nearly yearlong evaluation included two technical workshops held in Geneva, Switzerland in April and July 2016, where the second showcased the six most “meritorious” proposals for presentation to interested WHO Member States and relevant funders that are also named in the report.

“On behalf of the Biotechnology Innovation Organization (BIO), we congratulate SAB Biotherapeutics for this significant designation by the World Health Organization (WHO),” said Jim Greenwood, BIO President and CEO. “Continued investment in research & development is critical to prevent and combat epidemics. SAB’s immunotherapy platform is just one example of how cutting-edge technologies can lead to life-saving solutions.”

SAB's proposal was presented with LFB (France), Novavax, Inc. (U.S.), United States Naval Medical Research Center, (U.S.); CSIRO Health and Biosecurity Australian Animal Health Laboratory, (Australia) in collaboration to provide vaccine technology, pre-clinical testing protocols and facilities as well as clinical expertise.

“The best way to respond to an outbreak is to prepare before it happens,” added Sullivan. “With this global recognition, we are now seeking funding so these plans can be activated and the technologies are ready–during an epidemic threat–when we need them most.”

About SAB Biotherapeutics, Inc.

SAB Biotherapeutics, Inc. (SAB), headquartered in Sioux Falls, S.D. is a clinical stage, biopharmaceutical development company leading the science and manufacturing of antibody therapeutics. Utilizing some of the most advanced antibody science in the world, SAB is delivering the world’s first large-scale platform to create immunoglobulins. This natural production platform holds the potential for treatment of public health problems, rare conditions, long-term diseases and global pandemic threats.

About World Health Organization

The World Health Organization (WHO) is a specialized global agency whose primary role is to direct and coordinate international health within the United Nations system. It was established on 7 April 1948 and is headquartered in Geneva, Switzerland.

Contact information

SAB Biotherapeutics, Inc.
Melissa Ullerich, 605-695-8350
media@sabbiotherapeutics.com

Om Business Wire

Business Wire
Business Wire
24 Martin Lane
EC4R 0DR London

+44 20 7626 1982http://www.businesswire.co.uk

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Følg saker fra Business Wire

Registrer deg med din epostadresse under for å få de nyeste sakene fra Business Wire på epost fortløpende. Du kan melde deg av når som helst.

Siste saker fra Business Wire

AstraZeneca and Chi-Med’s Savolitinib Shows Encouraging Clinical Activity in 2nd-Line EGFR Mutation-positive Lung Cancer with MET-amplification16.10.2017 22:00Pressemelding

AstraZeneca and its partner Chi-Med today presented preliminary safety and clinical activity of savolitinib when given in combination with either Tagrisso (osimertinib) or Iressa (gefitinib) in two Phase Ib trials conducted in patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) with MET-amplification who had progressed following 1st-line treatment with an EGFR inhibitor.1,2 In both trials, the addition of savolitinib (600mg, once daily), an investigational selective inhibitor of c-MET (mesenchymal epithelial transition factor) receptor tyrosine kinase, to osimertinib (80mg, once daily) or gefitinib (250mg, once daily) demonstrated preliminary anti-tumour activity. The data were shared in two oral presentations at the International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan, 15-18 Oc

Orlando Melbourne Int’l (MLB) Lands Largest FAA Grant in Its History16.10.2017 21:34Pressemelding

When Air Force One landed at Orlando Melbourne International Airport (MLB) in February, Airport Executive Director Greg Donovan took advantage of the opportunity and advised the president of the United States that his 747-200 just landed on a commercial runway officially rated ‘poor’ in aviation terms. That’s going to change, thanks to an $18,132,588 FAA grant announced by U.S. Secretary of Transportation Elaine Chao today. This press release features multimedia. View the full release here: http://www.businesswire.com/news/home/20171016006292/en/ Greg Donovan, A.A.E. (Photo: Business Wire) “We asked for, and received, tremendous support from the Florida congressional delegation,” said Jack L. Ryals, chairman of the Melbourne Airport Authority. “We are deeply grateful to Congressman Posey, Senator Nelson and Senator Rubio for their advocacy on this critic

Colombia Selects IDEMIA to Upgrade Its Identification and Civil Registry Platform16.10.2017 14:34Pressemelding

IDEMIA, the global leader in trusted identities for an increasingly digital world, has been selected by the National Civil Registry of Colombia (Registraduría Nacional del Estado Civil de Colombia – RNEC 1 ) to update the identification and civil registry platform. This platform is the trusted repository of citizens’ biometric and alphanumeric data and ensures the uniqueness of identities. IDEMIA (formerly known as OT-Morpho) has worked with the RNEC since the beginning of this project and has constantly supported the successive improvements of the solution. In 2017, when in need to strengthen the platform in order to offer new services to the government and to the population while maintaining a high level of security and satisfaction of the users, RNEC decided to pursue its partnership with IDEMIA. Through this new contract, IDEMIA will e

ATB Financial Goes-Live on Murex’s SaaS Solution16.10.2017 14:00Pressemelding

Sibos - Murex, a global leader in trading, risk management and processing solutions, is pleased to announce the successful launch of the MX.3 SaaS solution at ATB Financial. MUREX SaaS is a managed services offering for the MX.3 platform, encompassing infrastructure and application management. This press release features multimedia. View the full release here: http://www.businesswire.com/news/home/20171016005092/en/ ATB pursued this initiative in order to create a simple yet comprehensive foreign exchange experience for their customers. In addition to the customer benefit, ATB was also able to rationalize their IT landscape, broaden the scope of financial instruments they provide on their digital platform, and prepare for a large volume increase in their trading activities. Due to the strength of the solution’s risk management capabilities, extensive asset class coverage, and the ra

Leave a review on print24.com and win a VW up!16.10.2017 13:59Pressemelding

The online print shop UNITEDPRINT SE, owner of renowned brands including print24.com, is asking its customers for their opinions on the company’s products and services. In return for their views, customers will receive vouchers and be entered into a prize draw. The online print shop is offering one voucher for every review submitted across various portals. The vouchers – worth up to €25.00 and valid until 31 March 2018 – will be subject to a minimum order amount (product price inc. VAT, not including delivery) of €250.00 per voucher. All reviews received up to 31 December 2017 will be eligible, regardless of length and content. You can learn more about the review campaign at https://print24.com/rate/ But not only that, print24.com is also giving every reviewer the chance to win a brand-new VW up! Ali Jason Bazooband, Managing Director for Innovation/Marketing at print24.com,

Bentley Systems Announces Winners of 2017 Be Inspired Awards16.10.2017 13:52Pressemelding

The Year in Infrastructure 2017 Conference – Bentley Systems, Incorporated, a leading global provider of comprehensive software solutions for advancing infrastructure, has announced the winners of the 2017 Be Inspired Awards. The annual awards program honors the extraordinary work of Bentley users advancing the world’s infrastructure. At a ceremony and gala at their Year in Infrastructure 2017 Conference, Bentley acknowledged 17 Be Inspired Awards winners and six Special Recognition Awards winners. The Year in Infrastructure Conference is Bentley’s annual global gathering of leading professionals in the world of infrastructure design, construction, and operations. In addition to thought-provoking keynotes, technology demonstrations, industry forums, and panel discussions, the agenda included presentations by finalists in the Be Inspired Awards program, culminating in the selection of t

I vårt presserom finner du alle våre siste saker, kontaktpersoner, bilder, dokumenter og annen relevant informasjon om oss.

Besøk vårt presserom