Reset Therapeutics, Inc. Establishes Research Collaboration With Alkermes for Discovery and Development of Novel Orexin Modulators
Reset Therapeutics, Inc., announced today a collaboration with an affiliate of Alkermes plc for the discovery, development and commercialization of novel orexin receptor modulators from Reset’s drug discovery platform. The orexin system is a key modulator of wakefulness, appetite and mood, and its dysregulation is associated with central nervous system (CNS) disorders such as narcolepsy and depression.
“Alkermes is an ideal partner with whom to advance this exciting program given the company’s success and expertise in the development and commercialization of CNS medicines,” said Ross Bersot, CFA, President and Chief Executive Officer of Reset Therapeutics. “Our orexin receptor modulator program is a prime example of how Reset is creating novel therapeutics by pursuing drug targets associated with the circadian system. Working together with Alkermes will accelerate advancement of this program, while Reset also pursues its cryptochrome modulator program and other opportunities in its pipeline.”
Under the terms of the agreement, Reset is providing Alkermes an exclusive, worldwide option to license orexin modulators resulting from the collaboration and Reset received an upfront fee and will be eligible to receive development, regulatory and sales-based milestone payments, as well as royalties on any future product sales. Reset will be fully responsible for the development of molecules arising from the collaboration through the completion of initial phase 2 clinical studies. Alkermes also made an equity investment in Reset.
“Alkermes has a strong commitment to identify and bring innovative CNS medicines to patients with critical unmet needs,” said Mark Namchuk, Ph.D., Senior Vice President of Research, Pharmaceutical and Nonclinical Development of Alkermes. “We are very pleased to initiate this research collaboration with Reset, leveraging the company’s unique insights into orexin receptor modulator chemistry and biology to explore the development of promising novel medicines for a range of CNS diseases.”
About Reset Therapeutics
Reset, a discovery-stage biopharma company co-founded by leaders in the field of circadian biology and Bay City Capital, is developing first-in-class approaches to treating diseases by restoring the body’s natural 24-hour, or circadian, rhythms. The company engineered a proprietary platform designed to identify and characterize compounds that modulate the activity and function of molecular clocks and discovers drugs that modulate these clocks and clock-controlled systems. Reset elucidates the connections between abnormal diurnal physiology and disease and has developed a burgeoning pipeline of potential new treatments that modulate these connections.
Reset Therapeutics, Inc.
Ross Bersot, 415-652-4953
Om Business Wire
Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.
Følg saker fra Business Wire
Registrer deg med din epostadresse under for å få de nyeste sakene fra Business Wire på epost fortløpende. Du kan melde deg av når som helst.
Siste saker fra Business Wire
Biogen and Eisai Expand Existing Collaboration Agreement to Develop and Commercialize Investigational Alzheimer’s Disease Treatments Including Phase 3 Aducanumab23.10.2017 11:15 | Pressemelding
Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (NASDAQ: BIIB) (Headquarters: Cambridge, Massachusetts, United States, CEO: Michel Vounatsos, “Biogen”) announced today that the companies have expanded their existing agreement to jointly develop and commercialize investigational Alzheimer’s disease treatments. This press release features multimedia. View the full release here: http://www.businesswire.com/news/home/20171023005462/en/ Under the terms of the agreement Eisai has exercised its option to co-develop and co-promote aducanumab, Biogen’s investigational anti-amyloid beta (Aβ) antibody for patients with Alzheimer’s disease (“AD”). The expanded agreement leverages each company’s respective geographic strengths for commercialization and adjusts the respective share of profits from potential sales of aducanumab. Biogen will receive 55
Open Letter from Mats Granryd, Director General, GSMA23.10.2017 11:01 | Pressemelding
Dear Ministers, As you are no doubt aware, European citizens and businesses rely on mobile networks to socialise, do business and access information everyday in every corner of every Member State of the Union. The social and economic activity that rides over this digital infrastructure drives economic growth, shapes future innovation and fosters more inclusive societies. As you prepare to convene at tomorrow’s Ministerial Council Meeting, I must express my grave concerns on the current state of discussions on the proposed European Electronic Communication Code (the Code). Although the European Union’s vision of a ‘Gigabit Society’, and recent discussions amongst the European Heads of State, demonstrate a strong ambition to recapture the region’s digital leadership and harness the full power of digital to drive growth, jobs and competitiveness, we do not see action foc
San Francisco 49ers and IDEMIA Announce Strategic Partnership to Enhance Fan Experience23.10.2017 09:30 | Pressemelding
The San Francisco 49ers and IDEMIA announced a new multi-year partnership to promote and implement identity and security services from IDEMIA’S IdentoGO solution, the country’s preeminent identity-related service provider and exclusive provider of TSA Pre✓®, at Levi’s® Stadium. In addition to offering TSA Pre✓® enrollment opportunities at 49ers home games, IDEMIA will equip the stadium with biometric-based technology to assist in fan experience and security in the near future. “We’re always looking for innovative ways to enhance security at Levi’s ® Stadium and IDEMIA’S IdentoGO technology complements our efforts as we strive to provide expedited entry for pre-approved customers,” said Jim Mercurio, 49ers Vice President of stadium operations and Levi’s® Stadium general manager. “We look forward to working with IDEMIA to jointly deploy the first-ever Trusted Fan Progr
E Ink and LTS Partner to Develop Smart Patch to Improve Medical Management23.10.2017 07:00 | Pressemelding
E Ink Holdings, "E Ink" (8069.TW), the leading innovator of electronic ink technology and LTS Lohmann-Therapie Systeme AG, “LTS” leading in the development and manufacturing of transdermal therapeutic systems, today announced their partnership to develop a “Smart Patch” prototype. The Smart Patch prototype is a transdermal therapeutic system (TTS) that delivers medication to patients in a convenient, controlled and comfortable manner and features an E Ink display to deliver and convey relevant information about patch performance. This press release features multimedia. View the full release here: http://www.businesswire.com/news/home/20171023005449/en/ The “Smart Patch” prototype features an E Ink display to convey relevant information about patch performance to patients. (Photo: E Ink Holdings) According to a report conducted by the New England Healthcare Institute
MaxLinear and Corinex to Use G.hn for Open Smart Metering Solution23.10.2017 06:00 | Pressemelding
MaxLinear, Inc. (NYSE:MXL), a leading provider of radio frequency (RF), analog and mixed-signal integrated circuits for the connected home, wired and wireless infrastructure, and industrial and multimarket applications and Corinex, a unique supplier of broadband solutions (BPL) for smart metering and smart grid infrastructure improving grid operational efficiency, security and integration of renewable energy and EV’s today announced that they will cooperate to create a broadband utility infrastructure solution based on standard ITU-T G.hn technology to enable smart metering and other smart grid applications. The G.hn solution will address the growing interest of electricity utilities in leveraging broadband powerline networks for Smart Grid applications, while ensuring multi-vendor interoperability, openness and easy integration into a wide range of Smart Meters and Smart Grid infrastr
NTT Communications to Share Industry Views with Global Carrier Community at Capacity Europe 2017 in London23.10.2017 06:00 | Pressemelding
Executives from NTT Communications (NTT Com), the global data and IP services arm of Fortune Global 500 telecom leader NTT (TYO: 9432), will play a prominent speaking role at this year’s Capacity Europe conference in London – Europe’s largest annual meeting for the global carrier community. During the conference, which runs October 24-26 at the Intercontinental London 02, NTT Com executives will participate in three panels that provide expert analysis and perspective on trending industry topics including the Internet of Things (IoT), network security and the importance of innovation and leadership. NTT Com is in a unique position to address global wholesale trends and opportunities as the global carrier consistently ranks as one of the top IP network providers worldwide. “Coming together as an industry to share insights and perspective is not only beneficia
I vårt presserom finner du alle våre siste saker, kontaktpersoner, bilder, dokumenter og annen relevant informasjon om oss.Besøk vårt presserom