Business Wire

New Survey Showed GI Health and Anti-Aging Benefits of Morinaga's Probiotics Milk with BB536

19.11.2015 17:00 | Business Wire

Del

Morinaga Milk Industry Co., Ltd. (TOKYO:2264), Japanese leading dairy product company, today unveiled the results of a nationwide survey jointly conducted with Tokyo Healthcare University in Japan on the health status of over 20,000 middle-aged to elderly men and women for the purpose of investigating the relationship between regular consumption of calcium-fortified milk containing Bifidobacterium longum BB536 and health status.

This Smart News Release features multimedia. View the full release here: http://www.businesswire.com/news/home/20151119005020/en/

The results reveal that subjects regularly consuming the probiotic milk were less likely to experience fractures and several diseases, and showed improvement in forgetfulness, quality of life in daily living, which supports the benefits of B. longum BB536 for anti-aging.

“The results obtained from this survey linked the continuous consumption of the probiotic milk supplemented with B. longum BB536 for reducing some disease risks, such as colon cancer, and in helping to prevent certain aging-related challenges of middle-aged to elderly people, in such areas as forgetfulness for example,” stated Dr. Taeko Shimoda, professor of Tenshi College, professor emeritus of Tokyo Healthcare University.

“Although other components in the milk, such as calcium, might have also contributed to the outcomes of the present survey, B. longum BB536 is believed to possess an important function from a point of view of improving intestinal health and the relationship with the gut-brain axis.”

The Survey Shows the Potential of Probiotic Milk Consumption for Anti-Aging

Questionnaires were distributed to middle-aged to elderly men and women aged in their 50s to 80s with or without experience of consuming “calcium fortified milk containing BB536,” from December 2013 to March 2014. A total of 92,110 questionnaires were distributed and 23,188 effective answers were received. Data analysis was performed by comparison between subjects with experience of the probiotic milk consumption for ≥ 3 years and for ≥4 times per week and subjects without experience of consumption of this probiotic milk.

Compared with the non-intake group, the probiotic milk-consuming group (intake group) showed the following;

  1. The proportions of subjects who had (a tendency to) constipation were lower in both men and women.
  2. The proportions of subjects who experienced forgetfulness (men and women), fatigue (women) and low back pain (women) in daily life were lower.
  3. The proportions of subjects who experienced colon polyp (men), kidney disease (women), liver disease (men) and gallstones (men) were lower.
  4. For women who had consumed the milk for over 10 years, fewer subjects experienced bone fractures in the past 5 years.

Risk for experiencing forgetfulness in daily life (Fig.1)

The result showed that there was a significant reduction of risk for forgetfulness by 19% (P = 0.03) and 14% (P = 0.002) for men and women, respectively, in the intake group compared to non-intake group.

B. longum BB536 (ATCC BAA-999) has been reported to be effective in normalizing anxiety-like behavior and hippocampal brain derived neurotrophic factor in mice with infectious colitis (Bercik et al., 2011). The present survey supported the possible effect of consumption of BB536 supplemented milk for improving brain health via the gut-brain axis.

Risk for developing a colon polyp

There was a significant reduction of risk for history development of a colon polyp by 26% (P = 0.003) for men in the intake group compared to non-intake group. B. longum BB536 has shown its effect in suppressing the development of carcinogenesis induced by carcinogen in male and female rats (Reddy and Rivenson,1993). In addition, intake of yogurt containing B. longum BB536 lowered the cell number of enterotoxigenic Bacteroides fragilis (ETBF), a bacteria which has been suggested to be associated with diarrheal disease, inflammatory bowel disease and colorectal cancer (Odamaki et al., 2012). The present survey suggests the possible effect of consumption of the probiotic milk supplemented with B. longum BB536 in lowering the risk of colon cancer.

Risk of experiencing bone fractures in the past 5 years

The proportion of history of bone fractures in the past 5 years was significantly lower in the intake group compared to non-intake group for women, with a significant reduction of risk for experiencing bone fractures by 16% (P = 0.04). The proportion of history of bone fractures in men was lower than that in women, and there was no significant difference between the intake and non-intake groups.

Igarashi et al. (1994) reported that a simultaneous administration of B. longum BB536 and milk calcium was more effective in improving the bone strength as compared to administration of calcium alone in rats. The present survey suggested the potential for B. longum BB536 in lowering the risk of bone fractures.

About BB536 and Morinaga

Bifidobacterium longum BB536 was isolated from human intestine and is one of the most thoroughly researched probiotic strains in the world. Morinaga has conducted research and development on BB536 for over 40 years, and achieved U.S. FDA-notified GRAS in 2009. Supported by over 110 published studies, BB536’s beneficial effects have been confirmed in such clinical areas as intestinal health, immunity, infection, and allergy.

Morinaga Milk Industry Co., Ltd. is the second largest dairy product company in Japan, founded in 1917 and employing 3,080 people. Morinaga has exhibited excellence in the field of technology and has offered not only dairy products but also other beneficial functional ingredients to the world for years. For more information, visit us at http://www.morinagamilk.co.jp/english/.

References

P. Bercik et al., The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication; Neurogastroenterol Motil. 23(12):1132-9 (2011)

S. Reddy and Abraham Rivenson, Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f] quinoline, a food mutagen; Cancer Research 53 : 3914-3918 (1993)

T.Odamaki et al., Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota; Anaerobe. 18(1)14-18 (2012)

M. Igarashi et al., Effect of Bifidobacterium longum and lactulose on the strength of bone in ovariectomized osteoporosis model rats; Bifidus 7 : 139-147 (1994)

Contact information

Morinaga Milk Industry Co., Ltd.
Mai Nozawa, +81-3-3798-0152
m-nozawa@morinagamilk.co.jp
http://www.morinagamilk.co.jp/english/

Om Business Wire

Business Wire
Business Wire
24 Martin Lane
EC4R 0DR London

+44 20 7626 1982http://www.businesswire.co.uk

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Følg saker fra Business Wire

Registrer deg med din epostadresse under for å få de nyeste sakene fra Business Wire på epost fortløpende. Du kan melde deg av når som helst.

Siste saker fra Business Wire

Biker Summer 2017 campaign: What’s happening during Biker Summer 2017? Moto-tyres.co.uk is giving away exciting prizes!18.8.2017 09:22Pressemelding

Whether it’s a short weekend break or a long-distance tour – once again this year Moto-tyres.co.uk is asking bikers from 10 countries about their dream destinations and longest journeys as part of its “Biker Summer 2017” campaign. To ensure than nothing gets in the way of your next tour, the two-wheeler tyre store from Delticom, Europe’s leading online tyre dealer, is entering anyone who completes the survey before 30 September 2017 into a prize draw to win some great biking accessories. Simply answer three short questions about your plans for bike tours this year (don’t forget to provide your name and email address), and with a bit of luck, you might win one of these great prizes. Up for grabs are a GARMIN motorbike GPS system, a GoPro camera with helmet bracket and five 200-Pound vouchers for new motorbike tyres from the online store – thanks to the product range at Moto-tyres.co.uk, eve

Lenovo Continues to Gain Momentum in First Quarter FY 2017/1818.8.2017 00:04Pressemelding

Behind the strength of its 3-wave strategy, Lenovo’s business transformation continued to gain traction during the first quarter, delivering solid profitability in its core PC and smart devices business, and revenue and profit improvements in targeted growth areas, including the data center and mobile businesses. Fueled by new investments in people and products, Lenovo’s Data Center Group (DCG) introduced the most comprehensive product lineup in its history, with the new ThinkSystem and ThinkAgile portfolio, and continued to build out its end-to-end sales organization. Similarly, Lenovo’s Mobile Business Group launched significant new products led by the Moto Z2 Force, available now on all major U.S. carriers, and ramped up its branding efforts worldwide. “In the first quarter this fiscal year, we had stable performance as we executed our 3-wave strategy with commitment. We

Spirent Tests Wi-Fi Network Performance with O2 at the Coca-Cola London Eye17.8.2017 15:57Pressemelding

Spirent Communications plc (LSE:SPT), today announced its Landslide E10 network test platform has been used with O2 to validate the Wi-Fi network performance and capacity at the Coca-Cola London Eye, before the launch of a new smartphone application last month. This Smart News Release features multimedia. View the full release here: http://www.businesswire.com/news/home/20170817005758/en/ Spirent Landslide E10 helped O2 validate Wi-Fi performance and capacity at the Coca-Cola London Eye, before the launch of a new smartphone application last month. (Photo: Busines Wire) Merlin Entertainments plc, operator of the London Eye, wanted to measure its Wi-Fi network performance, to ensure its infrastructure could provide an excellent experience for users of the new app, which puts increased demands on the Wi-Fi network. “The London Eye is a global attractio

Watch BizWireTV: A Camera You Can Wear and Krispy Kreme’s Famous Donuts Get Eclipsed with Chocolate17.8.2017 12:08Pressemelding

On BizWireTV, catch some Quick Biz Hits and see the latest in Star Power. Also see what’s happening in the startup world with the Accelerator Report, featuring the VC Watch and this week’s Startup Standout. This Smart News Release features multimedia. View the full release here: http://www.businesswire.com/news/home/20170817005305/en/ BizWireTV is hosted by Jordyn Rolling (Photo: Business Wire Now you can watch BizWireTV, and the latest breakthroughs in tech from the biggest brands, on any screen you want by downloading the new app through the Apple TV and iPhone App Store and Google Play for Android devices. Top of the Wire Introducing FrontRow: the camera re-invented. Watch BizWireTV to see more disruptors as well as the top 5 trending stories of the week! A core c

PsiOxus Therapeutics Announce Two New Board Appointments: New Board Appointments Strengthen Company’s US Presence17.8.2017 07:00Pressemelding

PsiOxus Therapeutics, Ltd. (PsiOxus) today announced the appointment of Charles Rowland and Duncan Higgons to the Board of Directors as part of an ongoing drive to expand in the US. Charles Rowland was most recently the President and Chief Executive Officer (CEO) of Aurinia Pharmaceuticals, a clinical stage pharmaceutical company focused on the global lupus nephritis market. Prior to this, he served as the Vice President and Chief Financial Officer (CFO) of ViroPharma, during which time the company grew into a global biopharmaceutical business with $500 million in annual revenues until it was acquired by Shire plc for $4.2 billion. Before joining ViroPharma, Mr. Rowland was executive Vice President, CFO, and interim co-CEO, for Endo Pharmaceuticals. In his earlier career, Charles held finance and operational positions at Biovail Pharmaceuticals, Breakaway Technologies, Pharmacia

Smarsh Adds Voice Archiving Offering with Acquisition of London-Based Cognia17.8.2017 06:59Pressemelding

Smarsh®, providing information archiving solutions for compliance, e-discovery and risk management, has completed the acquisition of Cognia, a worldwide leader in cloud-based voice archiving, audio search and analytics. Smarsh will leverage Cognia’s intellectual property and development resources to offer its global customer base enhanced capabilities around mobile and fixed-line voice communication – alongside a market-leading range of electronic communications – within The Archiving Platform. The acquisition will expand the existing presence of Smarsh in Europe and is central to its MiFID II compliance solution for financial firms. In addition to capturing incoming and outgoing communication from fixed-line recording solutions, Cognia uniquely captures voice content directly from leading mobile carriers. Carrier-direct capture is the most reliable and automated method for capt

I vårt presserom finner du alle våre siste saker, kontaktpersoner, bilder, dokumenter og annen relevant informasjon om oss.

Besøk vårt presserom