Eyenuk Inc.’s AI-Based Diabetic Retinopathy Screening Software EyeArt™ Tested with Portable Smartphone-Based Imaging Device in New Study Indicating Potential for Highly Sensitive Yet Cost-Effective Mass Retinal Screening
Eyenuk, Inc., a leading developer of advanced clinically supported artificial intelligence (AI) enabled solutions to identify diseases via retinal image analysis, today announced the publication of a study using Eyenuk’s EyeArt™ screening software on retinal images acquired with the Remidio Fundus on Phone (FOP) system, an FDA 510k registered fundus camera which combines a smartphone with patented optics. The study demonstrated very high sensitivity for detecting both any diabetic retinopathy (DR) and sight-threatening diabetic retinopathy (STDR), indicating potential for enabling highly sensitive yet cost-effective mass retinal screening.
The research, conducted at Madras Diabetes Research Foundation (MDRF) in Chennai, India, was published in the international ‘Eye’ journal (Springer Nature) by Dr. R. Rajalakshmi and her colleagues from MDRF. The study investigators chose Eyenuk’s EyeArt™ AI screening software to analyze retinal images of individuals with diabetes taken with a Remidio Fundus on Phone system. The EyeArt™ screening software results were compared to independent blinded grading by retinal specialists to evaluate the diagnostic efficacy. Sensitivity for detecting any DR and STDR was 95.8% and 99.1% respectively, while specificity was 80.2% and 80.4% respectively. The study authors noted that some non-DR retinal lesions like drusen, RPE atrophic patch, a retinal telangiectatic vessel at macula, RPE hypertrophy, tessellated fundus and retinal vein occlusion were the causes of false positives.
“We are very encouraged by this study demonstrating impressive sensitivity and specificity using EyeArt™ with images from this novel smartphone-based fundus imaging system. This is especially notable given that our AI system was never trained on images captured by the Remidio FOP system, suggesting the robustness and broad applicability of our software algorithms,” stated Kaushal Solanki, Founder & CEO of Eyenuk, Inc. “We look forward to converting these impressive results into real-world clinical practice by eventually making EyeArt™ available for mass diabetic retinopathy screening in conjunction with a lower-cost portable high-quality fundus imaging device like the Remidio system.”
According to the World Health Organization (WHO), there are nearly 285 million visually impaired people worldwide. As many as 80% of those cases could have been avoided with early detection. With 90% of those affected living in low-income areas, an effective, accessible, affordable, and easy-to-use screening system is critical for early detection of eye diseases such as diabetic retinopathy, which if untreated may lead to blindness. Combining EyeArt™ automated AI-based screening software with an affordable camera, such as the one offered by Remidio, may provide greater and less expensive access to eye screening around the world, and potentially reduce the incidence of blindness caused by diabetic retinopathy.
Until recently, diabetic retinopathy could only be detected by trained ophthalmologists and retina specialists who examine the back of the eye (retina) or by retinal color photography taken using expensive retinal cameras. Moreover, these retinal photographs had to be interpreted by trained eye doctors. Recently, advanced technologies like Remidio FOP that combine smartphones with sophisticated optics, have enabled cost-effective and high-quality retinal imaging that was not previously possible with basic smartphone attachments. Artificial intelligence, a simulation of intelligence by a software/machine, is a specialized field based on teaching the machine, via numerous examples, to accurately interpret the images. With recent advances in AI, pioneering tools like EyeArt™ can now be used to grade retinal images of people with diabetes to determine which patients have any retinopathy, or have sight-threatening retinopathy requiring urgent referral to an ophthalmologist.
Dr. V. Mohan, Chairman, Dr. Mohan’s Diabetes Specialities Centre and Director, MDRF said, “One out of 5 Indians with diabetes are at risk for developing diabetic retinopathy. Given the alarming increase in the number of people with diabetes and shortage of trained retinal specialists, computer-based analysis using artificial intelligence of the retinal photographs, taken using sleek and user-friendly smartphone-based cameras would reduce the burden of the health systems in screening for sight-threatening retinopathy. Use of artificial intelligence to analyze retinal images is a significant development and it fits in well with the current trend of using telemedicine to reach the remote underserved parts of the country especially the rural areas where specialized healthcare is often non-existent.”
Dr. R. Rajalakshmi, Head-Medical Retina, Dr. Mohan’s Diabetes Specialities Centre and MDRF said, “Regular retinal screening for all people with diabetes is still an unmet need in most countries especially in poor developing countries. Automated artificial intelligence software along with smartphone-based retinal imaging can be a promising initial tool for mass retinal screening.” She added that smartphone retinal color photography combined with an automated detection system can ideally result in models with potential for cost-effective routine clinical use by the primary care physicians.
Dr. Anand Sivaraman, CEO of Remidio Innovative Solutions Pvt. Ltd., said, “The simplicity achieved by combining smartphones with our patented optics has resulted in Remidio Fundus On Phone to be priced at 1/5th to 1/10th of any traditional desktop retinal imaging system, delivering high quality relevant images repeatedly with high sensitivity and specificity exceeding 92% and 98% when clinically validated. The use of artificial intelligence like EyeArt™ in screening the images from the Remidio Fundus on Phone device, now enables large scale public health screening for eye health among the 400 million affected by Diabetes, globally.”
ABOUT EYENUK, INC.
Eyenuk, Inc., headquartered in Los Angeles, California, is an AI diagnostic company focused on quickly and accurately identifying patients suffering from potentially blinding eye diseases and chronic diseases at the point of care. Using computer vision and machine learning expertise, the company is developing a portfolio of products based on its proprietary retinal image analysis technology combined with deep learning to identify and track the progression of diseases including diabetic retinopathy, glaucoma, age-related macular degeneration, risk of stroke, cardiovascular risk, and Alzheimer’s disease. EyeArt™ development was partially supported by prestigious National Eye Institute (NEI/NIH) grants (EB013585, EY026864, EY027241). EyeArt™ has received CE Marking and Health Canada approval, and is commercially available in the European Union and in Canada. In the United States, EyeArt™ is limited by federal law to investigational use only and is not available for sale. For more information, visit www.eyenuk.com.
ABOUT MADRAS DIABETES RESEARCH FOUNDATION:
Madras Diabetes Research Foundation (MDRF), a unique 100% nonprofit research centre exclusively devoted for advanced research on diabetes and its complications, was established in 1996. Madras Diabetes Research Foundation is recognized by the Indian Council of Medical Research (ICMR) as “ICMR Centre for Advanced Research on Diabetes.”
ABOUT REMIDIO INNOVATIVE SOLUTIONS PVT LTD:
Remidio is an innovative medical device company that seeks to create Healthcare Access by combining simplicity of product design with cutting edge technology and sustainable business model innovations. Remidio uses principles of Design Thinking and involves key stakeholders during the product development process – clinicians, patients, and health workers, with a view to designing product solutions that are simple to use, clinically relevant, reliable and scalable. Remidio’s CE marked and FDA 510k registered retinal imaging devices have helped screen and impact more than 7.5 million patients in 15 countries globally, as a result of increased access provided by the ease of use and affordability of Remidio’s patented optics on the smartphone platform.
Kevin Skol, +1 (707) 702-3585
Dr. V. Mohan, +91 44- 4396 8888
Dr. R. Rajalakshmi, +91 44- 4396 8888
Dr. Anand Sivaraman, +91 9845155475
Om Business Wire
(c) 2018 Business Wire, Inc., All rights reserved.
Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.
Følg saker fra Business Wire
Registrer deg med din epostadresse under for å få de nyeste sakene fra Business Wire på epost fortløpende. Du kan melde deg av når som helst.
Siste saker fra Business Wire
PSB Names Mike Chuter Chief Executive Officer18.12.2018 14:15 | Pressemelding
PSB, a global research-based consultancy within BCW, announced today that Mike Chuter has joined the firm as Chief Executive Officer, effective immediately. Chuter is based in New York and reports to Donna Imperato, Global CEO of BCW. He is responsible for the global growth and development of the organization across its Corporate, Political, Media and Entertainment practices. “Mike is exceptionally well-suited to lead PSB given his deep experience interpreting data through both analytical and creative lenses and in driving integrated communications programs rooted in analytics,” said Imperato. “Mike is the right person to help PSB advise on holistic creative communications solutions that leverage the firm’s industry-leading expertise in primary research and behavioral, social and other third-party data analysis.” Chuter is a 25-year agency veteran who joins PSB from global social impact organization Thankful, which he co-founded in 2013, a one-half commercial enterprise, one-half socia
The Keio Plaza Hotel Tama Creates New “Hello Kitty” Photographic Spot and Sanrio Characters Themed Rooms －“My Melody” and “Little Twin Stars”18.12.2018 14:05 | Pressemelding
The Keio Plaza Hotel Co., Ltd., one of Japan’s most prestigious hotel companies operating hotels located in the Shinjuku district of Tokyo and other locations, is proud to announce that it is fortifying its collaborative relationship with the Sanrio Co., Ltd. (Headquarters: Shinagawa, Tokyo, President and CEO: Shintaro Tsuji) to expand our facilities and services featuring “Hello Kitty” and other Sanrio characters at our Keio Plaza Hotel Tama facility. We will create a new photographic spot within our hotel lobby where guests can take pictures with “Princess Kitty” in March 2019, and renovate another four rooms to become Sanrio characters themed rooms, two rooms each in the themes of “My Melody” and “Little Twin Stars” (Kiki and Lala), in June 2019 in addition to the four existing “Hello Kitty” themed rooms. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181218005251/en/ In Keio Plaza Hotel Tama, a new photo spot based upon
Chartbeat Announces the Most Engaging Stories of 201818.12.2018 12:00 | Pressemelding
Chartbeat, the leading content intelligence platform for publishers, today announces the Most Engaging Stories of 2018, the articles that were read most this year based on highest Engaged Time. Selected from over 60 million pieces of content published on thousands of media sites around the world, the top stories serve as a snapshot of the year’s major events and highlight the themes that resonated most with readers. 2018 saw familiar political and social themes rise to the top, including Brexit, the Trump administration, the #MeToo movement, and climate change, but it was the deeply investigated and deeply personal stories of human struggle from publications like CNN, The New York Times, New York Magazine, and Rolling Stone that topped the list again this year. “Each year, the Most Engaging Stories list proves the power of storytelling. We learn more about the world, of course, but we also learn more about how to make sense of it and each other,” said John Saroff, CEO of Chartbeat. “Th
European DataWarehouse Launches Enhanced Private Data Environment18.12.2018 11:23 | Pressemelding
European DataWarehouse (ED) today announced it has launched an enhanced version of ED Private, a private data environment to report information including energy efficiency and relevant documentation for a variety of instruments such as credit claims, covered bonds, private cash and synthetic ABS transactions, ABCP, whole loan portfolios and private repo transactions. Built on EDitor, an integrated web application, ED Private offers easy and user-friendly access. The solution facilitates controlled transmission of designated information between the issuer, who is responsible for authorising access, and data users. Furthermore, ED Private provides a technical framework for accessing, uploading and downloading information on demand. The enhanced private data environment for documentation and transactions can be used to facilitate reporting to rating agencies, central banks, competent authorities and dedicated investors. The technical framework for the transmission and dissemination of the
ZT Acquires Both Mobile & IoT Messaging and Interact Business Units From NewNet18.12.2018 10:17 | Pressemelding
ZephyrTel, a division of ESW Capital focused exclusively on global telecommunications operators, is pleased to announce it has acquired the Interact and Mobile Messaging business units of NewNet Communication Technologies with immediate effect. The acquisition will integrate the Mobile Messaging, Invigorate Rating and Charging Platform and the Nimblevox Cloud IVR technology into the ZephyrTel rapidly growing Telecoms Cloud Portfolio. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181218005330/en/ ZephyrTel's CEO, Mike Shinya (Photo: Business Wire) ZephyrTel has built a world-class telecommunication Cloud software company to provide software solutions and services to the global telco industry. The company’s primary objective is to provide carrier-grade Cloud applications and Cloud enablement products. The goal being to deliver industry-leading throughput, robustness, scale and value to its customers at the pace they need. Zep
AccelStor Renews License Agreement with Login VSI18.12.2018 10:00 | Pressemelding
AccelStor, the manufacturer of award-winning all-flash arrays (AFAs), announced the multi-year renewal of the license agreement with Login VSI (www.loginvsi.com), the industry standard in VDI and SBC performance testing. Login VSI will be used in AccelStor’s R&D labs and Technical Marketing materials. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181218005030/en/ AccelStor Renews License Agreement with Login VSI (Photo: Business Wire) “We are committed to providing our VDI customers with the best possible end-user experience. This means we are 100% focused on the optimal performance and scalability of our solutions,” says Stefan Ferrari, Technical Sales Director of AccelStor. “The Login VSI software helps us build superior products and demonstrate the power of our solutions in an objective and industry standard way.” Login VSI will be used in the R&D laboratories of AccelStor in Taipei, Taiwan; Fremont, CA; and London, UK;