Celltrion and Yonsei University Health System Team up to Develop New Drugs for Cerebrovascular Diseases
On May 30, Celltrion (KRX:068270) signed an agreement with Yonsei University Health System on the joint development and license-in of Fc-Saxatilin, a candidate drug for ischemic strokes in a bid to develop new biopharmaceuticals for cerebrovascular diseases.
Under the agreement, Celltrion and Yonsei University Health System will conduct joint development for the optimization of the Fc-Saxatilin molecule, after which Celltrion will have an option for the exclusive worldwide license to conduct clinical trials, to obtain approvals, and to commercialize the drug.
Fc-Saxatilin, which is a new molecule developed by Professor Ji Hoe Heo-led team of the Severance Integrative Research Institute for Cerebral & Cardiovascular Diseases of Yonsei University with funding by the Ministry of Health and Welfare’s Healthcare Technology Research and Development Project, is expected to have superior efficacy and safety to existing treatments in terms of thrombolytic effect and lower side effects (cerebral hemorrhage) in patients with ischemic stroke (cerebral infarction) caused by the blocking of cerebral blood vessel.
The global market size of the diagnosis and treatment drugs for ischemic stroke is expected to grow 6.8% each year and to reach an estimated KRW 2.3 trillion by 20201. Currently, the only drug for ischemic stroke approved by major regulatory authorities is the thrombolytic agent Activase® (Alteplase) developed and marketed by Genentech in the U.S. If Celltrion succeeds in the joint development and commercialization of the new biopharmaceutical, the drug may be used together with or replace the current thrombolytic agent Activase®.
An executive of Celltrion said: “In order to bolster our next-generation pipeline, in addition to the development of antibody biosimilars, we have continued efforts to explore platform technologies and new molecules in relation to the development of new biopharmaceuticals and synthetic drugs.” He added: “Through the agreement with Yonsei University Health System, we will push for open innovation to secure new drug pipelines such as for cerebrovascular diseases, autoimmune diseases, breast cancer, etc.”
About Celltrion, Inc.
Headquartered in Incheon, Korea, Celltrion is a leading biopharmaceutical company, specializing in research, development and manufacture of biosimilar and innovative drugs. Celltrion strives to provide more affordable biosimilar mAbs to patients who previously had limited access to advanced therapeutics. Celltrion received FDA and EC’s approval for INFLECTRA® and Remsima®, respectively, which is the world’s first mAb biosimilar to receive approval from a regulatory agency in a developed country. For more information, visit www.celltrion.com.
Yonsei University Health System
Yonsei University Health System (YUHS) was founded in 1885 as the first modern medical institution in Korea. YUHS includes 3 colleges (Medicine, Dentistry, Nursing), graduate schools, and 4 hospitals named as Severance hospitals. The hospitals have around 3,700 beds and see around 3 million outpatients and 1 million inpatients annually. Based on more than 130 years of experience in medicine and scientific manpower in research fields, YUHS strives to achieve its goal of becoming the medical research hub through close cooperation.
1 TMR report 2014
About Business Wire
(c) 2018 Business Wire, Inc., All rights reserved.
Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Velodyne Lidar Acquires Mapper.ai for ADAS Launch23.7.2019 15:00:00 CEST | Press release
Velodyne Lidar, Inc. today announced it has acquired mapping and localization software as well as intellectual property assets from Mapper.ai. Mapper technology will enable Velodyne to accelerate development of Vella™, breakthrough software that establishes its directional view Velarray™ lidar sensor. The Velarray is the first solid-state Velodyne lidar sensor that is embeddable and fits behind a windshield, as an integral component for superior, more effective advanced driver assistance systems (ADAS). This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190723005257/en/ In addition to ADAS, Velodyne will incorporate Mapper technology into lidar-centric solutions for other emerging applications, including autonomous vehicles, last-mile delivery services, security, smart cities, smart agriculture, robotics, and unmanned aerial vehicles. (Photo: Business Wire) Mapper’s entire leadership and engineering teams will join Velodyne, bol
Gilead Presents New Findings on Profile of Descovy® for Potential Use as HIV Pre-exposure Prophylaxis Compared With Truvada®23.7.2019 15:00:00 CEST | Press release
Gilead Sciences, Inc. (NASDAQ: GILD) today presented additional results from the DISCOVER trial evaluating an investigational use of Descovy (emtricitabine 200 mg and tenofovir alafenamide 25 mg tablets; F/TAF) for HIV pre-exposure prophylaxis (PrEP). In a sub-analysis of the DISCOVER trial, Descovy reached intracellular drug concentration levels above the estimated protective threshold significantly more quickly than Truvada (emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg tablets; F/TDF), and additional pharmacokinetic data confirm that these drug concentration levels persist longer than Truvada. The results were presented at the 10th International AIDS Society Conference on HIV Science (IAS 2019) being held in Mexico City. “Gilead is committed to driving advances in HIV prevention and supporting broader public health initiatives that are designed to reduce HIV infections,” said Diana Brainard, MD, Senior Vice President, HIV and Emerging Viruses, Gilead Sciences. “These
Wealthy Americans are increasingly willing to invest, new UBS survey finds23.7.2019 14:12:00 CEST | Press release
US high net worth individuals and business owners are expressing growing intentions to invest as US markets continue to hit record highs in 2019, according to UBS Global Wealth Management's new quarterly Investor Sentiment survey. The survey, which polled more than 3,800 wealthy investors and entrepreneurs in 17 countries, also shows US investors remain positive on the U.S. stock market but continue to rank politics and the national debt as top concerns. Fifty percent of US investors see a diversified portfolio as a hedge against US-China trade tensions specifically, in line with UBS GWM's own views, compared with 41% who favor cash. Filippo Ilardi, US Client Strategy Officer at UBS Global Wealth Management, says: "We are pleased to see a substantial increase in investors willing to put more money in the market. Wealthy Americans are concerned about the political environment and US-China trade tensions but we are encouraged that they see diversification as an important way of managing
Andersen Global Expands into Ghana23.7.2019 13:30:00 CEST | Press release
Ghana law firm, Sam Okudzeto & Associates, signed a collaboration agreement with Andersen Global, marking Andersen Global’s presence in 13 African countries and over 51 countries worldwide. Located in the capital of Accra, Sam Okudzeto & Associates is one of the largest law firms in Ghana. For the past 48 years, the firm has provided legal advice and guidance in the corporate and commercial areas, including patents and trademarks, mergers and acquisition, tax advisory, corporate banking, international trade and investment, debt recovery, mining and mineral law, industrial and labor, aviation, maritime law, petroleum oil and gas, and intellectual property. Sam Okudzeto & Associates founder and Managing Partner, Sam Okudzeto and Nene Amegatcher, have led the team since the establishment of the firm until Nene Amegatcher was elevated to the Supreme Court. The firm now has four partners and 18 lawyers who have gained international reputation for their keen knowledge and experience with Alt
Seoul Semiconductor Switches to Rimini Street for SAP Support23.7.2019 13:00:00 CEST | Press release
Rimini Street, Inc. (Nasdaq: RMNI), a global provider of enterprise software products and services, the leading third-party support provider for Oracle and SAP software products and a Salesforce partner, today announced that Seoul Semiconductor, a global LED development and manufacturing company headquartered in South Korea, has switched from SAP to Rimini Street for support of its SAP ECC 6.0 system. As a result, Seoul Semiconductor has been able to reduce its annual maintenance fee by 50%, enjoy better support and can continue operating its stable, robust ERP ECC 6.0 system for a minimum of 15 additional years from the date the company switched to Rimini Street to retain full support without any forced upgrades or product migrations. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190723005031/en/ Seoul Semiconductor, a global LED development and manufacturing company headquartered in South Korea, has switched from SAP to R
Experiments Demonstrate Seoul Semiconductor SunLike Series Natural Spectrum LEDs Enhance Crop Yields, Antioxidant Content23.7.2019 13:00:00 CEST | Press release
Seoul Semiconductor Co., Ltd. (KOSDAQ 046890), a leading global innovator of LED technology, announced the results of a series of experiments that demonstrated a higher growth rate and higher flavonol (antioxidant) content in crops grown under SunLike Series natural spectrum LEDs than those grown under standard white LEDs. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190723005037/en/ SunLike Series LEDs Experiment Results on Crop Yields and Antioxidant Content (Graphic: Business Wire) The experiments were conducted on lettuce using SunLike Series LED lighting and standard white LED lighting of the same color temperature and light intensity. After two weeks of crop growth, the fresh weight and flavonol content of the lettuce were measured and compared. The fresh weight of lettuce grown under SunLike Series LEDs came in at 43.0g, 13.5% higher than the yield produced by standard white LEDs. In addition, the flavonol content h